Hieronder vindt u het overzicht van de wetenschappelijke publicaties waar medewerkers van het FAGG aan meegewerkt hebben.
| Datum publicatie | Artikel/advies | Tijdschrift/overheidsinstelling | Auteurs |
| 2026 | Review on organs-on-chips for medicines safety assessment: A European regulatory perspective |
ALTEX. 43(1): 98-112 |
Joana M.D. Portela, Polly Paul, Orla Moriarty, Peter Theunissen, Sonja Beken, Susanne Brendler-Schwaab, Corinne de Vries, Stefano Ponzano |
| 2026 | From animal testing to model-informed drug development: building on ICH M15 and EMA initiatives to make new approach methodologies (NAMs) deliver | Frontiers in Pharmacology. doi: 10.3389/fphar.2026.1877947 | Jean-Michel Dogné, Médéa Locquet, Flora Musuamba, Sonja Beken |
| 2026 | Revisiting ICH S7A after 25 years: Outcomes of a multi-stakeholder workshop and strategic pillars for modernizing safety pharmacology | Regulatory Toxicology and Pharmacology. doi: 10.1016/j.yrtph.2026.106096 |
Jean-Pierre Valentin, Sonja Beken, Yasunari Kanda, Derek Leishman, Jennifer B Pierson, Colleen M Pike, Jan Turner |
| Datum publicatie | Artikel/advies | Tijdschrift/overheidsinstelling | Auteurs |
| 07.10.2025 | The impact of the European Medicines Agency (EMA) and the Heads of Medicines Agencies (HMA) to address shortages of human and veterinary medicines across Europe | Frontiers in Public Health | Inga Abed, Vanessa Bennett, Brendan Cuddy, Sandra Dang, Juan García Burgos, Domenico Di Giorgio, Maria Lamas, Momir Radulovic, Nuno Simões, Rui Santos Ivo, Hugues Malonne, Monica Dias |
| 26.07.2025 | Evaluation of Awareness of Photosensitivity Risk and Additional Risk Minimisation Measures for Ketoprofen Gel in Belgium and Luxembourg | Drugs - Real World Outcomes | Veselina Skrinska-Kirilova, Javier Sawchik, Martine Sabbe, Martine Debacker, Guy Weber, Anne-Cécile Vuillemin & Jamila Hamdani |
| 10.02.2025 | From guideline to practice: three years of ICH S11 insights and recommendations | Frontiers in Medicine | Diana Tavares, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter van Meer, Karen Van Malderen |
|
2025 |
ALTEX. 2025;42(2):204-223 |
Uwe Marx, Sonja Beken, Zaozao Chen, Eva-Maria Dehne, Ann Doherty, Lorna Ewart, Suzanne C Fitzpatrick, Linda G Griffith, Zhongze Gu, Thomas Hartung, James Hickman, Donald E Ingber, Seiichi Ishida, Jayoung Jeong, Marcel Leist, Lisa Levin, Donna L Mendrick, Giorgia Pallocca, Stefan Platz, Marian Raschke, Lena Smirnova, Danilo A Tagle, Martin Trapecar, Bas W M van Balkom, Janny van den Eijnden-van Raaij, Andries van der Meer, Adrian Roth |
|
|
2025 |
New approach Methodologies: EU regulatory horizons | Nature Reviews Drug Discovery 24(8): 571-572 |
Mariana Edwards, Oriane Blanquie, Orla Moriarty, Sonja Beken, Falk Ehmann |
| Datum publicatie | Artikel/advies | Tijdschrift/overheidsinstelling | Auteurs |
| 18.03.2024 |
Inherited retinal dystrophies and orphan designations in the European Union |
European Journal of Ophthalmology | Jane Moseley, Tim Leest, Kristina Larsson, Armando Magrelli, and Violeta Stoyanova-Beninska |
| 09.01.2024 | Stem Cell Reports - ISSCR | Surat Parvatam,David Pamies, Francesca Pistollato, Sonja Beken, Indumathi Mariappan, Adrian Roth, Monica Piergiovanni, Benoıt G.C. Maisonneuve, Lorna Ewart, Abhijit Majumder, Prajakta Dandekar, Rahul Date, Kasturi Mahadik, Saravanan Thiyagarajan, and Sandra Coecke | |
|
2024 |
Role of standards and funding in accelerating the development and use of microphysiological systems |
ALTEX. 2024;41(4):669-670 |
Surat Parvatam, Harshita Mittal, Francesca Pistollato, Kasturi Mahadik, Lorna Ewart, Abhijit Majumder, Y K Gupta, Sonja Beken, Rajeshwari Adheseshan, Glyn Stacey, Vishal Gandhi, Dhiraj Kumar, Helder Constantino, Goutami Nayak, Tejaswini Ghurde, Mousumi Gupta, Alokparna Sengupta, Troy Seidle |
| 2024 | Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems |
Stem Cell Reports. 19(1):37-40 |
Surat Parvatam, David Pamies, Francesca Pistollato, Sonja Beken, Indumathi Mariappan, Adrian Roth, Monica Piergiovanni, Benoît G C Maisonneuve, Lorna Ewart, Abhijit Majumder, Prajakta Dandekar, Rahul Date, Kasturi Mahadik, Saravanan Thiyagarajan, Sandra Coecke |
|
2024 |
Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development | Advanced Biology (Weinh). 2024 Aug;8(8):e2300131 |
Lindsay Tomlinson, Diane Ramsden, Sofia Batista Leite, Sonja Beken, Jessica A Bonzo, Paul Brown, Pelin L Candarlioglu, Tom S Chan, Eugene Chen, Colin K Choi, Rhiannon David, Nathalie Delrue, Patrick J Devine, Kevin Ford, Martha Iveth Garcia, James R Gosset, Philip Hewitt, Kimberly Homan, Onyi Irrechukwu, Anna K Kopec, Jennifer L Liras, Sandhya Mandlekar, Arek Raczynski, Nakissa Sadrieh, Melanie Z Sakatis, Jeffrey Siegel, Kyung Sung, Ilona Sunyovszki, Terry R Van Vleet, Jason E Ekert, Rhiannon N Hardwick |
| Datum publicatie | Artikel/advies | Tijdschrift/overheidsinstelling | Auteurs |
| 10.11.2023 | Substandard and falsified ivermectin tablets obtained for self-medication during the COVID-19 pandemic as a source of potential harm. | National Library of Medicine National Center for Biotechnology Information |
Celine Vanhee, Bram Jacobs, Angélique Kamugisha, Michael Canfyn, Hans Van Der Meersch, Bart Ceyssens, Eric Deconinck, Koenraad van Hoorde, Marie Willocx |
| 22.07.2023 | Uncovering the Quality Deficiencies with Potentially Harmful Effects in Substandard and Falsified PDE-5 Inhibitors Seized by Belgian Controlling Agencies | Forensic sciences | Celine Vanhee, Bram Jacobs, Marcella Mori, Angélique Kamugisha, Loïc Debehault, Michael Canfyn, Bart Ceyssens, Hans Van Der Meersch, Koenraad van Hoorde, Eric Deconinck and Marie Willocx |
| 27.04.2023 | EMA commentary on the ICH guideline for testing for carcinogenicity of pharmaceuticals | Brit J Clinical Pharma | Jan Willem van der Laan, Mikael Andersson, Sonja Beken, Milton Bonelli, Susanne Brendler-Schwaab, Rosemary Kane, Markku Pasanen, Stefano Ponzano, Jakob Paur, Christine Siezen, Anne Soleng, Rhys Whomsley |
|
07.04.2023 |
Drug Saf. 2023 Apr;46(4):391-404. doi: 10.1007/s40264-023-01281-9. Epub 2023 Apr 7. | Monika Raethke, Florence van Hunsel, Nicolas H Thurin, Caroline Dureau-Pournin, Dirk Mentzer, Barbara Kovačić, Nikica Mirošević Skvrce, Evelien De Clercq, Martine Sabbe, Gianluca Trifirò, Nicoletta Luxi, Alexia Giovanazzi, Saad Shakir, Olaf H Klungel, Sandor Schmikli, Miriam Sturkenboom | |
|
2023 |
EMA commentary on the ICH guideline for testing for carcinogenicity of pharmaceuticals | British Journal of Clinical Pharmacology. 89(8):2341-2348 |
Jan Willem van der Laan, Mikael Andersson, Sonja Beken, Milton Bonelli, Susanne Brendler-Schwaab, Rosemary Kane, Markku Pasanen, Stefano Ponzano, Jakob Paur, Christine Siezen, Anne Soleng, Rhys Whomsley |
|
2023 |
3Rs implementation in veterinary vaccine batch-release testing: Current state-of-the-art and future opportunities. A webinar and workshop report | Biologicals. 83:101695 |
Laura Viviani, Elisabeth Balks, Sonja Beken, Anna-Maria Brady, Rick Clayton, Florence Cliquet, Liys Desmayanti, Silvia Fragoeiro, Terrie Jo Hamtak, David John, Carmen Jungbaëck, M Kalaivani, Imke Kross, Catherine Lang, Ni Made Ria Isriyanthi, Laurent Mallet, Catherine Milne, Michelle Rubbrecht, Botond Siklódi, Brajesh Singh, Geetha B Srinivas, Paul Stickings, Catrina Stirling, Pushpanathan Sundram, Mária Szabó, Anne Thomas, Mariette van den Berg, Angela Walker, Corinne Philippe, Joris Vandeputte |
|
2023 |
Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum | Regulatory Toxicology and Pharmacology. 144:105483 |
Mark T D Cronin, Nicholas Ball, Sonja Beken, Hans Bender, Ofelia Bercaru, Laura Caneva, Marco Corvaro, Richard A Currie, Jeffrey L Dawson, Paul Desert, Sylvia E Escher, Antonio Franco, Amaia Irizar, Jyotigna M Mehta, Vera Rogiers, Raphaël T Tremblay, Carl Westmoreland, Gavin Maxwell |
| Datum publicatie | Artikel/advies | Tijdschrift/overheidsinstelling | Auteurs |
| 02.06.2022 | Survey on the use of benzodiazepines and Z-drugs to treat insomnia in Belgium | Federal Agency for Medicines and Health Products | Sophie Kiridis (FAMHP), Javier Sawchik (FAMHP), Nele Maenhaut (FAMHP), Martine Sabbe (FAMHP), Françoise Wuillaume (FAMHP), Jamila Hamdani (FAMHP) |
| 16.02.2022 |
Use and misuse of prescription stimulants by university students: a cross-sectional survey in the french-speaking community of Belgium | National Library of Medicine National Center for Biotechnology Information |
Martine Sabbe, Javier Sawchik, Mégane Gräfe, Françoise Wuillaume, Sara De Bruyn, Pierre Van Antwerpen, Guido Van Hal Martin Desseilles, Jamila Hamdani, Hugues Malonne |
| 21.01.2022 | Reliable and Scalable SARS-CoV-2 qPCR Testing at a High Sample Throughput: Lessons Learned from the Belgian Initiative | Life |
Van Vooren S, Grayson J, Van Ranst M, Dequeker E, Laenen L, Janssen R, Gillet L, Bureau F, Coppieters W, Devos N, Hengchen B, Wattiau P, Méhauden S, Verlinden Y, Van Baelen K, Pattery T, Valentin JP, Janssen K, Geraerts M, Smeraglia J, Hellemans J, Wytynck P, Mestdagh P, Besbrugge N, Höfer R, Nollet F, Vandesompele J, De Smet P, Lebon J, Vandewynckele E, Verstrepen S, Uten W, Capron A, Malonne H, Poels J, André E |
| 2022 | Organ-on-a-chip: current gaps and future directions | Biochemical Society Transactions. 50(2):665-673 | Pelin L Candarlioglu, Gianni Dal Negro, David Hughes, Frances Balkwill, Kate Harris, Hazel Screen, Hywel Morgan, Rhiannon David, Sonja Beken, Olivier Guenat, Wendy Rowan, Augustin Amour |
| 01.10.2021 | Safety, Immunogenicity and Interchangeability of Biosimilar Monoclonal Antibodies and Fusion Proteins: A Regulatory Perspective | Drugs | Pekka Kurki, Sean Barry, Ingrid Bourges, Panagiota Tsantili, Elena Wolff Holz |
| 01.10.2021 | Evaluating Diagnostic Accuracy of Saliva Sampling Methods for Severe Acute Respiratory Syndrome Coronavirus 2 Reveals Differential Sensitivity and Association with Viral Load | J Mol Diagn | Pieter Mestdagh, Michel Gillard, Sharonjit K Dhillon, Jean-Paul Pirnay, Jeroen Poels , Jan Hellemans Veronik Hutse, Celine Vermeiren, Maxime Boutier, Veerle De Wever, Patrick Soentjens, Sarah Djebara, Hugues Malonne, Emmanuel André, Marc Arbyn, John Smeraglia, Jo Vandesompele |
|
09.08.2021 |
International Society of Blood Transfusion | Jana Vanden Broeck, Katrien Beeckman, Evelyne Van Gastel, Luc De Keersmaecker, Timothy Devos, Christiane Gérard, Lucien Noens, Dominique Putzeys, Karin Van Poucke, Margareta Haelterman, Véronique Deneys, Rik Schots | |
| 24.03.2021 |
Diagnostic and analytical performance evaluation of ten commercial assays for detecting SARS-Co |
Journal of Immunological Methods |
Marnix Mylemans, Eveline Van Honacker, Louis Nevejan, Stefanie Van Den Bremt, Laura Hofman, Jeroen Poels, Lien Cattoir, An Boel, Lieve Van Hoovels |
| 15.10.2020 | Evaluation of the effectiveness of direct healthcare professional communication regarding new dosage of paracetamol paediatric syrup |
Pharmacoepidemiology and Drug Safety |
Françoise Wuillaume, Martine Sabbe, Javier Sawchik, Jamila Hamdani |
| 10.04.2020 | Survey on prescription stimulant use among university students in Wallonia and Brussels: prevalence, motives and perceived effects Survey performed in October 2018 |
Federal Agency for Medicines and Health Products |
Javier Sawchik, Martine Sabbe, Mégane Gräfe |
| 10.01.2019 | Borstimplantaat-geassocieerd anaplastisch grootcellig lymfoom (breast implant associated-anaplastic large cell lymphoma, bia-alcl) |
Hoge Gezondheidsraad |
Decaluwe Kelly; De Mey Albert |
| 29.10.2019 |
International Journal of Toxicology |
Jan Willem van der Laan, Karen van Malderen, Nico de Jager, Dinah Duarte, Gunter F. Egger, Fabien Lavergne, Cláudio Gouveia Roque, Isabel Vieira, Lutz Wiesner, and Jacqueline Carleer |
|
05.2018 |
Randomized clinical trials and observational studies in the assessment of drug safety | Rev Epidemiol Sante Publique; 66(3):217-225 | Sawchik J, Hamdani J, Vanhaeverbeek M. |
|
10.2017 |
Recruitment barriers for prophylactic vaccine trials: a study in Belgium | Vaccine | Lauriane Harrington, , Pierre Van Damme, , Corinne Vandermeulen, Stéphanie Mali |
|
07.2017 |
Acute kidney injury in the critically ill still remains a challenge |
European Medical Journal p 92 - 100 |
Karin Janssen van Doorn |
|
2017 |
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects |
Critical Reviews in Toxicology, 7(5):402-414 |
Peter T Theunissen, Sonja Beken, Bruce Beyer, William J Breslin, Gregg D Cappon, Connie L Chen, Gary Chmielewski, Luc de Schaepdrijver, Brian Enright, Jennifer E Foreman, Wafa Harrouk, Kok-Wah Hew, Alan M Hoberman, Julia Y Hui, Thomas B Knudsen, Susan B Laffan, Susan L Makris, Matthew Martin, Mary Ellen McNerney, Christine L Siezen, Dinesh J Stanislaus, Jane Stewart, Kary E Thompson, Belen Tornesi, Jan Willem Van der Laan, Gerhard F Weinbauer, Sandra Wood, Aldert H Piersma |
|
2017 |
Biology-inspired Microphysiological Systems to Advance Patient Benefit and Animal Welfare in Drug Development | ALTEX, 37(3):364-394 |
Uwe Marx, Takafumi Akabane, Tommy B Andersson, Elizabeth Baker, Mario Beilmann, Sonja Beken, Susanne Brendler-Schwaab, Murat Cirit, Rhiannon David, Eva-Maria Dehne, Isabell Durieux, Lorna Ewart, Suzanne C Fitzpatrick, Olivier Frey, Florian Fuchs, Linda G Griffith, Geraldine A Hamilton, Thomas Hartung, Julia Hoeng, Helena Hogberg, David J Hughes, Donald E Ingber, Anita Iskandar, Toshiyuki Kanamori, Hajime Kojima, Jochen Kuehnl, Marcel Leist, Bo Li, Peter Loskill, Donna L Mendrick, Thomas Neumann, Giorgia Pallocca, Ivan Rusyn, Lena Smirnova, Thomas Steger-Hartmann, Danilo A Tagle, Alexander Tonevitsky, Sergej Tsyb, Martin Trapecar, Bob Van de Water, Janny Van den Eijnden-van Raaij 7, Paul Vulto, Kengo Watanabe, Armin Wolf, Xiaobing Zhou, Adrian Roth |
| 2017 | Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation |
Regulatory Toxicology and Pharmacology 113, 14624 (Epub) |
Helen Prior, Paul Baldrick, Sonja Beken, Helen Booler, Nancy Bower, Paul Brooker, Paul Brown, Brian Burlinson, Leigh Ann Burns-Naas, Warren Casey, Melissa Chapman, David Clarke, Lolke de Haan, Olaf Doehr, Noel Downes, Meghan Flaherty, Nichola Gellatly, Sophia Gry Moesgaard, Jennifer Harris, Mark Holbrook, Julia Hui, David Jones, Keith Jones, Hilla Kedar, Andreas Mahl, Alli Manninen, Aidan McGuire, Elisabeth Mortimer-Cassen, Marjorie Peraza, Michael K Pugsley, Jacques Richard, Ruth Roberts, Wendy Roosen, Andreas Rothfuss, Ankie Schoenmakers, Fiona Sewell, Richard Weaver, Lucinda Weir, Alison Wolfreys, Ian Kimber |
| 2017 | Building confidence in skin sensitization potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019 |
Regulatory Toxicology and Pharmacology 117:104767 |
D. Basketter, S. Beken, H. Bender, J. Bridges, S. Casati, M. Corvaro, S. Cuvellier, B. Hubesch, A. Irizar, M.N. Jacobs, P. Kern, F. Lamplmair, I. Manou, B.P. Müller, R. Roggerbrand, L.H. Rossi |
| 10.2016 | Cell-based therapies for cardiac repair: a meeting report on scientific observations and European regulatory viewpoints. | Eur J Heart Fail. 2016 Feb;18(2):133-41. doi: 10.1002/ejhf.422. Epub 2015 Oct 16. | Schüssler-Lenz M, Beuneu C, Menezes-Ferreira M, Jekerle V, Bartunek J, Chamuleau S, Celis P, Doevendans P, O'Donovan M, Hill J, Hystad M, Jovinge S, Kyselovič J, Lipnik-Stangelj M, Maciulaitis R, Prasad K, Samuel A, Tenhunen O, Tonn T, Rosano G, Zeiher A, Salmikangas P. |
| 10.2016 | Residues in Beeswax: A Health Risk for the Consumer of Honey and Beeswax? | Journal of Agricultural and Food Chemistry website | Co-auteur: Bruno Urbain |
| 10.2016 | Clarification on the naming of a VMP and the use of standard terms |
Regulatory Rapporteur |
Valérie Van Merris, Hedi Hellenurm-Sepp |
| 10.2016 | Marketing authorisation transfer to a mutual recognition procedure for a veterinary product | Regulatory Rapporteur |
Valérie Van Merris, Johan Vanlerberghe, |
| 02.2016 | Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges | mAbs Journal, 8(3), 427-45. De Smet K. and Van Aerts A., Non-clinical studies for biosimilars (2017) Eds Endrenyi, Declerck and Chow,Taylor and Francis. | Chapman K., Adjei A., Baldrick P., da Silva A., De Smet K., DiCicco R., Hong S.S., Jones D., Leach M., McBlane J., Ragan I., Reddy P., Stewart D., Suitters A. and Sims J. |
|
2016 |
ALTEX. 33(3):272-321 |
Uwe Marx, Tommy B Andersson, Anthony Bahinski, Mario Beilmann, Sonja Beken, Flemming R Cassee, Murat Cirit, Mardas Daneshian, Susan Fitzpatrick, Olivier Frey, Claudia Gaertner, Christoph Giese, Linda Griffith, Thomas Hartung, Minne B Heringa, Julia Hoeng, Wim H de Jong, Hajime Kojima, Jochen Kuehnl, Marcel Leist, Andreas Luch, Ilka Maschmeyer, Dmitry Sakharov, Adrienne J A M Sips, Thomas Steger-Hartmann, Danilo A Tagle, Alexander Tonevitsky, Tewes Tralau, Sergej Tsyb, Anja van de Stolpe, Rob Vandebriel, Paul Vulto, Jufeng Wang, Joachim Wiest, Marleen Rodenburg, Adrian Roth |
|
|
2016 |
Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals |
Validation of alternative methods for toxicity testing, Eds. M. Whelan and C. Eskes, Springer, 27 September 2016:33-64 |
Sonja Beken, Peter Kasper, Jan-Willem van der Laan |
|
2016 |
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects |
Critical Reviews in Toxicology, 46(10):900-910 |
Peter T Theunissen, Sonja Beken, Bruce K Beyer, William J Breslin, Gregg D Cappon, Connie L Chen, Gary Chmielewski, Luc De Schaepdrijver, Brian Enright, Jennifer E Foreman, Wafa Harrouk, Kok-Wah Hew, Alan M Hoberman, Julia Y Hui, Thomas B Knudsen, Susan B Laffan, Susan L Makris, Matt Martin, Mary Ellen McNerney, Christine L Siezen, Dinesh J Stanislaus, Jane Stewart, Kary E Thompson, Belen Tornesi, Jan Willem Van der Laan, Gerhard F Weinbauer, Sandra Wood 3, Aldert H Piersma |
|
11.2015 |
Therapeutic Innovation & Regulatory Science |
J. Stewart, W. J. Breslin, B. K. Beyer, K. Chadwick, L. De Schaepdrijver, M. Desai, B. Enright, W. Foster, J. Y. Hui, G. J. Moffat, B. Tornesi, K. Van Malderen, L. Wiesner, and C. L. Chen |
|
| 08.2015 | Advies 8866 -Analyse van de globale toxiciteit van aluminium en blootstellingsberekening met eenbijzondere aandacht voor aluminiumverbindingen in cosmetica | Hoge Gezondheidsraad | K. De Smet |
| 14.07.2015 | Advies 12-2015 –Betreft: Residuen van gewasbeschermingsmiddelen en van diergeneesmiddelen in bijenwas : scenarioanalyse van de chronische blootstelling van de consumenten en voorstel van actielimieten (SciCom 2014/13) | AFSCA | De werkgroep was samengesteld uit: Leden van het Wetenschappelijk Comité: C. Saegerman (verslaggever), P. Delahaut, P. Gustin, A. Legrève, M.-L. Scippo, W. Steurbaut Externe experten: D. de Graaf (UGent), B.K. Nguyen (ULg – GxABT), W. Reybroeck (ILVO), B. Urbain (FAGG) Dossierbeheerder: O. Wilmart (FAVV) De activiteiten van de werkgroep werden opgevolgd door de volgende leden van de administratie: C. Rettigner (FAVV) en C. Vinkx (FOD Volksgezondheid, Veiligheid van de Voedselketen en Leefmilieu) |
| 04.2015 | Advanced Therapy Medicinal Products: How to Bring Cell-Based Medicinal Products Successfully to the Market - Report from the CAT-DGTI-GSCN Workshop at the DGTI Annual Meeting 2014. | Transfus Med Hemother. 2015 May;42(3):194-9. doi: 10.1159/000382107. Epub 2015 Apr 28. | Celis P, Ferry N, Hystad M, Schüßler-Lenz M, Doevendans PA, Flory E, Beuneu C, Reischl I, Salmikangas P. |
| 2015 | Paracetamol use during pregnancy and child neurodevelopment | Dev Med Child Neurol, 57(8), 718-24 | Defays L., Van Malderen K., De Smet K., Verlinden V., Hamdani J., Sawchick J., Dogné J.-M. andDan B. |
|
2015 |
“Open Source”–Based Engineered Human Tissue Models: A New Gold Standard for Nonanimal Testing Through Openness, Transparency, and Collaboration, Promoted by the ALEXANDRA Association |
Applied In vitro Toxicology, 1, 1, pp. 5-9 |
Bart De Wever, Alan Goldberg, Chantra Eskes, Erwin Roggen, Philippe Vanparys, Klaus Schröder, Béatrice Le Varlet, Howard Maibach, Sonja Beken, Benoit De Wilde, Constantin Turchina, Ginette Bogaert, Jean-Pierre Bogaert |
|
2015 |
Removing Obstacles on the Way to Implement 3R Methods in Toxicology: Regulatorys Point of View |
Toxicology Letters, 282, 2, S3 |
Sonja Beken |
| 2015 | Knowledge sharing to facilitate regulatory decision-making in regard to alternatives to animal testing: Report of an EPAA workshop |
Regulatory Toxicology and Pharmacology, 73(1): 210-226T |
Tzutzuy Ramirez, Sonja Beken, Magda Chlebus, Graham Ellis, Claudius Griesinger, Sandra De Jonghe, Irene Manou, Annette Mehling, Kerstin Reisinger, Laura H Rossi, Jan van Benthem, Jan Willem van der Laan, Renate Weissenhorn, Ursula G Sauer |
|
2015 |
Impact Analysis of ICH S9 on Non-Clinical Development of Anticancer Drugs |
Regulatory Toxicology and Pharmacology, 73(1) 361-366 |
Milton Bonelli, Francesca Di Giuseppe, Sonja Beken |
| 2014 | Animal studies in non-clinical development of biosimilars – a paradigm shift in the EU | mAbs Journal, 6(5), 1155-1162 | Van Aerts A., De Smet K., Reichmann G., van der Laan J.W. and Schneider C. K. |
| 2014 | Generic chiral method development in SFC and ultra-performance SFC | Journal of Chromatography A 1363 (2014) 311-322 | Katrijn De Klerck, Yvan Vander Heyden and Debby Mangelings |
| 2014 | Pharmaceutical enantiomer resolution using immobilized polysaccharide-based chiral stationary phases in supercritical fluid chromatography | Journal of Chromatography A 1328 (2014) 85-97 | Katrijn De Klerck, Debby Mangelings, and Yvan Vander Heyden |
| 2014 | Exploratory data analysis as a tool for similarity assesment and clustering of chiral polysaccharide-based systems in supercritical fluid chromatography | Journal of Chromatography A 1326 (2014) 110-124 | Katrijn De Klerck, Debby Mangelings, and Yvan Vander Heyden |
| 2014 | Three versus five µm chlorinated polysaccharide-based packings in chiral capillary electrochromatography: efficiency and precision evaluation | Journal of Biomedical Chromatography 28 (2014) 68-81 | Ans Hendrickx, Katrijn De Klerck, Debby Mangelings, Lies Clincke, and Yvan Vander Heyden |
| 2014 | Three versus five µm chlorinated polysaccharide-based packings in chiral capillary electrochromatography: performance evaluation | Journal of Biomedical Chromatography 28 (2014) 182-191 | Ans Hendrickx, Katrijn De Klerck, Debby Mangelings, Lies Clincke, and Yvan Vander Heyden |
|
2014 |
Journal of Meat Science 96 (2) (2014) 821-828 | Evelinde De Mey, Katrijn De Klerck, Hannelore De Maere, Lore Dewulf, Guy Derdelinckx, Marie-Christine Peeters, Ilse Fraeye, Yvan Vander Heyden and Hubert Paelinck | |
|
2014 |
Impact of Silver Nanoparticles on Haemolysis, Platelet Function and Coagulation |
Nanobiomedicine, 4(7):1-9 |
Julie Laloy, Valentine Minet, Lutfiye Alpan, François Mullier, Sonja Beken, Olivier Toussaint, Stéphane Lucas, Jean-Michel Dogné |
|
2014 |
Regulatory Toxicology and Pharmacology, 69:41-48 |
Marie-Jeanne W A Schiffelers, Bas J Blaauboer, Wieger E Bakker, Sonja Beken, Coenraad F M Hendriksen, Herman B W M Koëter, Cyrille Krul |
|
|
2014 |
Reproductive Toxicology 47:27-32 |
Peter Theunissen, Sonja Beken, Gregg Cappon, Connie Chen, Alan Hoberman, Jan-Willem van der Laan, Jane Stewart, Aldert Piersma |
| 27.12.2013 | Omentum is better site than kidney capsule for growth, differentiation, and vascularization of immature porcineβ-cell implants in immunodeficient rats | Transplantation. 2013 Dec27;96(12):1026-33 | Bartholomeus K, Jacobs-Tulleneers-Thevissen D, Shouyue S, Suenens K, In't Veld PA, Pipeleers-Marichal M, Pipeleers DG, Hellemans K. |
| 2013 | Recent advances in SFC for the analysis of chiral and achiral pharmaceuticals | LC/GC Europe Supplement (May 2013) 'Advances in pharmaceutical analysis' | Katrijn De Klerck, Debby Mangelings and Yvan Vander Heyden |
| 2013 | Updating a generic screening approach in sub- or supercritical fluid chromatography for the enantioresolution of pharmaceuticals | Journal of supercritical fluids 80 (2013) 50-59 | Katrijn De Klerck, Christophe Tistaert, Debby Mangelings and Yvan Vander Heyden |
| 2012 | Enantioselectivity of polysaccharide-based chiral stationary phases in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases | Journal of Chromatography A 1269 (2012) 336-345 | Katrijn De Klerck, Greet Parewyck, Debby Mangelings and Yvan Vander Heyden |
| 2012 | Supercritical fluid chromatography for the enantioseparation of pharmaceuticals | Journal of Pharmaceutical and Biomedical Analysis 69 (2012) 77-92 | Katrijn De Klerck, Debby Mangelings and Yvan Vander Heyden |
| 2012 | Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography | Journal of Chromatography A 1234 (2012) 72-79 | Katrijn De Klerck, Debby Mangelings, David Clicq, Filip De Boever and Yvan Vander Heyden |
| 08.2010 | Human islet cell implants in a nude rat model of diabetes survive better in momentum than in liver with a positive influence of beta cell number and purity | Diabetologia. 2010 Aug;53(8):1690-9 | Jacobs-Tulleneers-Thevissen D, Bartholomeus K, Suenens K, Vermeulen I, Ling Z, Hellemans KH, In't Veld P, Pipeleers-Marichal M, Pipeleers D. |
| 03.2010 | Challenges with advanced therapy medicinal products and how to meet them. | Nat Rev Drug Discov. 2010 Mar;9(3):195-201. doi: 10.1038/nrd3052. Review. | Committee for Advanced Therapies (CAT); CAT Scientific Secretariat, Schneider CK, Salmikangas P, Jilma B, Flamion B, Todorova LR, Paphitou A, Haunerova I, Maimets T, Trouvin JH, Flory E, Tsiftsoglou A, Sarkadi B, Gudmundsson K, O'Donovan M, Migliaccio G, Ancāns J, Maciulaitis R, Robert JL, Samuel A, Ovelgönne JH, Hystad M, Fal AM, Lima BS, Moraru AS, Turcáni P, Zorec R, Ruiz S, Akerblom L, Narayanan G, Kent A, Bignami F, Dickson JG, Niederwieser D, Figuerola-Santos MA, Reischl IG, Beuneu C, Georgiev R, Vassiliou M, Pychova A, Clausen M, Methuen T, Lucas S, Schüssler-Lenz M, Kokkas V, Buzás Z, MacAleenan N, Galli MC, Linē A, Gulbinovic J, Berchem G, Fraczek M, Menezes-Ferreira M, Vilceanu N, Hrubisko M, Marinko P, Timón M, Cheng W, Crosbie GA, Meade N, di Paola ML, VandenDriessche T, Ljungman P, D'Apote L, Oliver-Diaz O, Büttel I, Celis P. |
| 2008 | Layer-by-Layer coated digitally encoded microcarriers allow sensitive quantification of proteins in serum and plasma | Analytical Chemistry 2008, 80, 85-94 | S. Derveaux, B. Stubbe, C. Roelant, M. Leblans, B. De Geest, J. Demeester, S.C. De Smedt* |
| 2008 | Advanced Functional Materials 2008, 18(11), 1624-1631 | B.G. Stubbe, S. Gevaert, S. Derveaux,K. Braeckmans, B.G. De Geest, M. Goethals, J. Vandekerckhove, J. Demeester, S.C. De Smedt* | |
| 2008 | Analytical and Bioanalytical Chemistry 2008, 391(7), 2453-2467 | S. Derveaux, B.G. Stubbe, K. Braeckmans, C. Roelant, J. Demeester, S.C. De Smedt* |
|
2007 |
Influence of free chains on the swelling pressure of PEG-HEMA and dex-HEMA hydrogels |
International Journal of Pharmaceutics 2007, 337, 31-39 |
T.G. Van Thienen, F. Horkay, K. Braeckmans, B.G. Stubbe, J. Demeester, S.C. De Smedt |
|
2007 |
Digitally encoded drug tablets to combat counterfeiting |
Advanced Materials 2007, 19(22), 3854-3858, With comments in:Nature Materials (Research Highlicht, December 2007) |
F. Fayazpour, B. Lucas, N. Huyghebaert, K. Braeckmans, S. Derveaux, B.G. Stubbe, J.P. Remon, J. Demeester, C. Vervaet, S.C. De Smedt |
| 09.2007 | Development and application of a simplified clean-up procedure for the determination of polychlorinated biphenyls and polybrominated diphenyl ethers in horse fat by gas chromatography – tandem mass spectrometry | Rapid Communications in Mass Spectrometry 18 (2004) 2317-2322 | C. Naert and C. Van Peteghem |
| 02.2007 | Distribution of polychlorinated biphenyls and polybrominated diphenyl ethers in birds of prey from Switzerland | Chemosphere 68 (2007) 977-987 | C. Naert, C. Van Peteghem, J. Kupper, L. Jenni and H. Naegeli |
|
2006 |
Self-exploding lipid coated microgels |
Biomacromolecules 2006, 7, 371-379 |
B.G. De Geest, B.G. Stubbe, A.M. Jonas, T. Van Thienen, W.L.J. Hinrichs, J. Demeester, S.C. De Smedt |
|
2006 |
Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation - a case study for fluorescein |
Journal of Biomedical Optics 2006, 11(4), 044013 |
K. Braeckmans, B.G. Stubbe, K. Remaut, J. Demeester, and S. C. De Smedt |
| 02.2006 | Occurrence of polychlorinated biphenyls and polybrominated diphenyl ethers in Belgian human adipose tissue | Archives of Environmental Contamination and Toxicology 50 (2006) 290-296 | C. Naert, M. Piette, N. Bruneel and C. Van Peteghem |
| 10.09.2004 | Development of a gas chromatograpy/ion trap mass spectrometry based method for the quantification of polybrominated diphenyl ethers and polychlorinated biphenyls in adipose tissue | Rapid Communications in Mass Spectrometry 18 (2004) 2317-2322 | C. Naert, S. De Saeger and C. Van Peteghem |
| 2004 | Modeling the swelling pressure of degrading hydroxyethylmethacrylate-grafted dextran hydrogels | Journal of Polymer Science-part B: Polymer Physics 2004, 42, 3397-3404 | B.G. Amsden, B. Stubbe, F. Horkay, S.C. De Smedt, J. Demeester |
| 2004 | Swelling pressure of hydrogels that degrade through different mechanisms |
Macromolecules 2004, 37, 8739-8744 |
B. Stubbe, W.E. Hennink, S.C. De Smedt*, J. Demeester |
|
2004 |
“Programmed polymeric devices” for pulsed drug delivery |
Pharmaceutical Research 2004, 21, 1732-1740 |
B. Stubbe, S.C.De Smedt*, J. Demeester |
| 2003 | Tailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels | Biomacromolecules 2003, 4, 691-695 | B.G. Stubbe, F. Horkay, B. Amsden, W.E. Hennink, S.C. De Smedt*, J. Demeester |
| 2002 | Swelling Pressure Observations on Degrading dex-HEMA Hydrogels | Macromolecules 2002, 35, 2501-2505 | B. G. Stubbe, K. Braeckmans, F. Horkay, W.E. Hennink, S.C. De Smedt*, J. Demeester |
| 2002 | A comparison between the use of dynamic mechanical analysis and oscillatory shear rheometry for the characterisation of hydrogels | International Journal of Pharmaceutics 2002, 244, 163-168 | T.K.L. Meyvis, B.G. Stubbe, J. Van Steenbergen, W.E. Hennink, S.C. De Smedt , J.Demeester |
| 2001 | The in Vitro Evaluation of ‘Azo Containing Polysaccharide Gels’ for Colon Delivery | Journal of Controlled Release 2001, 75, 103-114 | B. Stubbe, B. Maris, G. Van den Mooter, S.C. De Smedt* and J. Demeester |